Metabolic Dysfunction–Associated
Steatohepatitis (MASH)
Steatohepatitis (MASH)

A Chronic Liver Disease
MASH is a leading cause of liver-related mortality and an increasing burden on global healthcare systems.
The Role of Thyroid Hormone Receptor β (THR-β) in MASH
In MASH, reduced signaling via THR-β exacerbates hepatic mitochondrial dysfunction, inflammation, and fibrosis.


The Role of Thyroid Hormone Receptor β (THR-β) in MASH
In MASH, reduced signaling via THR-β exacerbates hepatic mitochondrial dysfunction, inflammation, and fibrosis.

Melody.education
Learn more about MASH with educational programs and podcasts (non-CME) presented by leading MASH experts. Be sure to become a member to receive regular updates on new content and test your knowledge with Clinician Challenge questions.
COMING SOON
Our Research
MAESTRO Clinical Development Program
Our clinical development program focuses on a thyroid hormone receptor-β (THR-β) agonist being studied for the treatment of MASH.
Publications
View key resmetirom and clinical publications along with recent congress presentations.